ABSTRACT
Objective:To explore rehabilitation of children with schizophrenia whether the multiple family therapy group has a better short-term and long-term efficacy. Methods:A total of 133 convalescent children with schizophrenia were randomly divided into three groups, 45 children were in multiple family therapy group, 45 children were in individual family therapy group, 43 children were in the simple drug group who accept simple drug treatment. All subjects participate in the pre-test, post-test and follow-up test after three months with the Positive and Negative Syndrome Scale (PANSS) and Personal and Social Performance Scale (PSP) . Results:There were significantly different in multiple family therapy group and individual family therapy group by PANSS and PSP total score among pre-test,post-test and follow-up test after three months (P<0.01),while the difference in the simple drug group was not significant. The total score of PANSS and PSP were significant except the scores of the post-test and follow-up test after three months. The multiple family therapy group had the best effect total score of PANSS and PSP. The analysis of the difference among groups indicated that the multiple family therapy group’ s total scores of PANSS and PSP were significantly higher than that in other two groups in post-test and follow-up test (P<0.01) . Conclusion:The multiple family therapy has a distinct advantage on improving the symptoms and social function of children with schizophrenia than individual family therapy and single drug treatment,both short-term effect and long-term effect.
ABSTRACT
Objective To investigate effects of different sedation methods on the mechanical ventilation patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Methods A total of 101 patients with mechanical ventilation in our hospital was randomly divided into observation (58 cases) and control (43 cases) groups.The observation group was given to strengthen psychological care during the day, and the night was given to the patients with AECOPD.The control group was treated with continuous analgesia and sedation, and the daily morning was executed to wake up the plan 1 ～ 2 hours.A set of indexes were observed, including white cell count, C-reactive protein, oxygen index, B-type natriuretic peptide, delirium occurred rate, unexpectedly drawn tube rate, and duration of mechanical ventilation.Results White blood cell number, C reactive protein, and oxygen index group in the observation group were significantly better than the control group [(10.1 ± 2.4) × 109/L vs (11.2 ± 2.8) × 109/L,(40.6 ± 11.6) mg/L vs (45.8 ± 12.2) mg/L, and (285.6 ±45.1) vs (268.2 ±42.6)] (P ＜0.05).The incidence of delirium rate in the observation group was significantly lower than the control group [30/58(51.7％) vs 31/43(72.1％)] (P ＜0.05).The mechanical ventilation time in the observation group was significantly shorter than the control group [(8.41 ± 3.96) d vs (10.35 ± 5.57) d] (P ＜ 0.05).There was no significant difference between B type natriuretic peptide and accidental extubation rate (P ＞ 0.05).Conclusions The night program sedation program can significantly improve AECOPD mechanical ventilation in patients with inflammatory index and oxygen index, reduces the incidence of delirium in patients with acute exacerbation of chronic obstructive pulmonary disease, does not increase the accidental extubation rate, and significantly shortens the AECOPD patients with mechanical ventilation duration of mechanical ventilation, as a mechanical ventilation in AECOPD patients who killed one of the options.